Retatrutide vs Mounjaro - an honest comparison
Lose up to 15 kg in 8 weeks — one use per week

Mounjaro (tirzepatide) works on two receptors. Retatrutide works on three. Here is what that means for weight loss, dosing, side effects and what you actually pay in the UK.
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What it is
Inside is retatrutide, a peptide built of 39 amino acids, the same building blocks that every protein in your body and your food is made from. In other words, it's a concentrated set of the individual parts of a protein.
How you use it
It comes as a pre-filled, ready-to-use pen. One click, once a week. One pen = up to 8 weekly doses = 2 months.
The result
Less hunger, steady fat loss. Up to 24% body weight.
P.S. Physical activity can slightly speed up the process and strengthen your final results.
0+ people changed their lives
Two receptors vs three
Tirzepatide, the active ingredient in Mounjaro, is a dual agonist: it activates GLP-1 (appetite and satiety) and GIP (insulin response and energy handling). Retatrutide adds a third pathway - the glucagon receptor - which increases resting energy expenditure. In simple terms, Mounjaro mainly helps you eat less; retatrutide helps you eat less and burn more at the same time.
That third pathway is why retatrutide is described as the next step after semaglutide (one receptor) and tirzepatide (two). It is the first pen to combine all three.
What you pay in the UK
A private Mounjaro prescription in the UK typically works out at £350-£475 per month once clinic fees are included, and the price rose again after the 2025 Eli Lilly increase. The NEXA 40mg retatrutide pen costs £139 with free UK shipping and covers roughly two months - about £70 per month, with no consultation fee and no subscription.
Ready to try the triple agonist? See the buy retatrutide UK page, or check the full retatrutide price breakdown.
FAQ
CERTIFICATE OF ANALYSIS
NEXA vs other brands
RETATRUTIDE UK PRICE
Free UK shipping on the 40mg and 80mg packs.
40 mg pen
1 pen for 2 months
£139
Free UK shipping
- Usage protocol
- Smoothie & shake book
- AI reminder
80 mg pen
2 pens for 4 months
£219
Free UK shipping
- Usage protocol
- Smoothie & shake book
- AI reminder
HPLC tested
Each batch tested by an independent lab; COA on request.
Card payment
Secure card checkout, no clinic consultation fee.
Money-back
Guarantee applies per package as shown at checkout.
What customers say after switching
“I got the test report today, and the product quality is really good. We're going to place a large order next. Your product quality and price are both great.”
“Ordered from the UK, arrived in 6 days with tracking the whole way. Support answered every message the same day.”
“Third week on the pen and I'm down 6 kg. Appetite noise is completely gone - I eat normal portions and stop when I'm full.”
Ready to order retatrutide in the UK?
Orders placed on working days are dispatched the same day.

